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Objective@#To investigate the methods and outcomes of surgical treatment for hip dislocation with cerebral palsy (CP) via soft tissue release, hip reduction and osteotomy.@*Methods@#Nineteen CP patients (male: 9, female: 10; total 23 hips) with hip dislocation underwent reconstructive surgery between April 2010 and December 2016. The average age was 12.5±2.4 years. There were 17 diplegic, 1 hemiplegic and 1 quadriplegic patient. Gross motor function classification system distribution were type I in 2 patients, type II in 10 patients, type III in 5 patients, type IV in 2 patients. Combine one-stage surgical procedures included soft tissue release, close or open reduction of hip joint and femoral varus shortening or de-rotational osteotomy and pelvic osteotomy. During the follow-up period, the clinical symptom and radiological parameters including Sharp angle and acetabular index were recorded.@*Results@#The average follow-up duration was 2.1 years (1-4.5 years). The radiological parameters were evaluated at one year postoperatively. The migration percentage corrected to 6%±8% from 68%±21% with statistically significant different (t=12.760, P<0.001). The mean Sharp angle was 42°±8.9°, which was statistically significant reduced compared with the pre-operative value 59°±6.1° (t=9.058, P<0.001). In 15 patients with triradiate cartilage open, the acetabular index also improved from 34°±8.7° pre-operatively to 18°±10° with statistical significance (t=5.598, P<0.001). Total of 15 patients had gained hip stability and improved functional status. Hip pain, which happened in 11 patients preoperatively, all had relieved after operation. Four patients had dissatisfied results and re-subluxation happened in 3 hips. All of them had CE angle <20° immediately after operation (average, 17°±2.6°), which was significantly different compared with average CE angle 32°± 8.0° in non-recurrence hips (t=3.143, P=0.005). One patient, who underwent proximal hamstring release, had decline of function status and contralateral hip dislocation.@*Conclusion@#Dislocation hips in CP patients can be effectively treated with one stage soft tissue release, hip reduction and femoral and pelvic osteotomy. The selection of osteotomy method is based on the age and pathological changes of patients.
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OBJECTIVE: To explore the effect of psychological restoration methods on antianxiety of middle-aged patients after percutaneous transcoronary angioplasty (PTCA) and stenting. METHODS: From August 2005 to October 2008, 60 patients underwent PTCA and stenting in First Affiliated Hospital of Xinxiang Medical College were selected, who had heart function of grade 1 or 2, certain capacities of understanding and self-care. They were randomly divided into two groups, namely, intervention group (24 males and 6 females, aged46-59 years) and control group (23 males and 7 females aged 46-58 years). The patients in the Intervention group received different psychological restoration according to their condition before and after surgery and psychological education for their anxiety, horror, depression and self-abasement. The patients in the control group were treated using normal methods. The anxiety extent of the patients before and after operation in two groups was assessed with Zung Self Rating Anxiety Scale (SAS) and Symptom Checklist 90 (SCL-90). High scores represented high extent of anxiety. RESULTS: The 60 patients were included in the final analysis. The scores of two scales in intervention group before and after intervention were significantly less than control group (P < 0.01). The scores of SAS on the day of operation were significantly reduced than before operation in intervention group (P < 0.01), and postoperative scores were significantly reduced compared with those on the day of operation (P < 0.01 ). In addition, some factors of SCL-90 in intervention after operation were similar to national norm and significantly reduced than preoperative scores (P < 0.01 ). CONCLUSION: Mental intervention treatment can significantly improve anxiety degree of patients undergoing PTCA and stenting and promote restoration of patients.
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Objective To study the genotoxicity of 3 kinds of different brands shampoo to Vicia faba root tip cells. Methods To take root tip cells of Vicia faba as the subjects,genetic safety tests were conducted on those materials treated with shampoo of a certain concentration(0.25% ) for 2-8 h of continual mutagenesis and accumulative mutagenesis respectively,micronucleus and chromosomal aberration was observed and calculated,the rate of tap water was used as the control. Results Three kinds of shampoo could induce root tip cells of Vicia faba to produce micronucleus and chromosomal aberration,the peak was in the continual mutagenesis for 4 h and accumulative mutagenesis for 8 h respectively,which showed dose-effect relationship. There were significant differences between the control group and the experimental groups( P
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Objective To study the genetic toxicity of 3 brands of detergents to the root tip cells of Vicia faba in the inducing time and the inducing way(continual mutagenesis,accumulative mutagenesis) with micronucleus and the chromosomal aberration Methods The root tip cells of Vicia faba were taken as the subjects,the genetic safety tests were conducted on those materials treated with detergent of a certain concentration(0.25%) for 2、4、6 h of continual mutagenesis and accumulative mutagenesis respectively.Distilled water was used as the control.Results The continual mutagenesis showed that all the three detergents could induce the root tip cells of Vicia faba to produce micronucleus and chromosomal aberration and as the mutagenic time prolonged,at 6 h,the changes became weak.The genetic toxicity in the accumulative mutagenesis group was greater than that in the continual mutagenesis group.Conclusion According to the results of the present paper,to some extent,detergents may produce genetic toxicity.
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Objective To study the genetic toxicity of magnesium sulfate to the root tip cells of Vicia faba. Methods The root tip cells of Vicia faba with 1.5-2 cm root tip were taken as the subjects and were exposed to magnesium sulfate of different concentrations(0.50%-2.00%) for 6 h. In the other test,the cells were treated with 1.5% magnesium sulfate for 2,4,6,8 and 10 hours respectively. The distilled water and potassium dichromate (0.05%) were used as the negative and positive control respectively. The micronucleus and the chromosomal aberration were calculated after 24 hours of culture. Results Compared with the negative control group,0.1%,0.15%,0.175% and 0.2% of magnesium sulfate increased the micronucleus and 0.05%,0.1%,0.15%,0.175%,0.2% of magnesium sulfate increased the chromosomal aberration in Vicia faba root tip cells. Compared with the control group (0 h),both of the micronucleus and the chromosomal aberration of Vicia faba root tip cells increased (P